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Concentrated Dark Matter was a fuel that Rick invented to travel faster than anyone else in the universe.
The Zigerions wanted the secret to making this fuel badly, and constantly tried to trick Rick into giving it to them but for years he continually outsmarted them. In "M. Night Shaym-Aliens!", the Zigerions attempted to trick Rick once more by trapping him within several levels of a simulated reality. Rick eventually is tricked into revealing the recipe to concentrated dark matter to a simulation of Morty. However, it is revealed after Rick leaves back to Earth that he lied about the ingredients needed, resulting in the Zigerions and their space ship exploding when they attempt to make the dark matter using Rick's phony recipe.
It can be assumed that Rick's ship ran on Concentrated Dark Matter or some type of derivative fuel.