|First seen in:||Pilot|
|Main voice actor:||Kari Wahlgren|
Morty has an obvious crush on her, but Jessica doesn't acknowledge Morty frequently. So far, she has only spoken to him directly once. In the Pilot, when Rick and Morty escape from Intergalactic Customs, the duo crash into her table. Jessica seems impressed and asks Morty on whether he just came through a portal. Rick, however, quickly drags Morty away.
In the episode "Rick Potion No. 9" Morty wanted to ask her out to the flu season dance, but before she could give him an answer, Brad came up and told Morty that she was out of his league and proceeds to walk off with her (much to her exasperation). She was later seen at the dance and Morty purposely touched her arm with the love potion serum making her fall in love with him, unfortunately she transmitted it (through sneezing) to everyone else in the school building. She was last seen mutated along with everyone else while still under the effects of the love potion in dimension C-137. In the episode "Ricksy Business", Rick and Morty's current dimension, she appears to be normal just like the previous dimensions Jessica was before she was turned into a cronenberg in "Rick Potion No.9".
- Jessica vaguely resembles her voice actor.
|Characters of Rick and Morty|
|Sanchez-Smith Family||Rick Sanchez • Morty Smith • Beth Smith • Jerry Smith • Summer Smith • Leonard Smith • Joyce Smith • Mrs. Sanchez • Morty Jr.|
|Harry Herpson High School||Jessica • Brad • Nancy • Mr. Goldenfold • Gene Vagina • Frank Palicky|
|Alternate Ricks||Cowboy Rick • Cronenberg Rick • Doofus Rick • Evil Rick • The Scientist Formerly Known as Rick|
|Alternate Mortys||Cronenberg Morty • Evil Morty|
|Characters of the Day||Prince Nebulon • Kevin • Annie • Ethan • Dr. Xenon Bloom • Poncho • Roger • Ruben • Mr. Meeseeks • Abradolf Lincler • King Jellybean • Scroopy Noopers • King Flippy Nips • Lucius Needful • Lucy • Snuffles • Squanchy • Birdperson|